BDBM50371060 CHEMBL226646

SMILES Cc1nnc(o1)-c1ccc(nn1)N1CCC(CC1)Oc1cc(F)ccc1Cl

InChI Key InChIKey=WFOFPVXMPTVOTJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50371060   

TargetAcyl-CoA desaturase 1(Mus musculus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50371060(CHEMBL226646)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of SCD1 in ob/ob mouse liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50371060(CHEMBL226646)
Affinity DataIC50: <10nMAssay Description:Inhibition of SCD in human NCI-H1155 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50371060(CHEMBL226646)
Affinity DataIC50: <10nMAssay Description:Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50371060(CHEMBL226646)
Affinity DataIC50:  670nMAssay Description:Inhibition of SCD1 in human HepG2 cells assessed as ratio of cellular protein product over substrate after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed