BDBM50372114 CHEMBL404646

SMILES COc1cccc(c1)-c1nc(CCOc2cccc(C[C@H]3[C@H](N(C3=O)c3ccc(cc3)C(C)(C)C)C(O)=O)c2)c(C)o1

InChI Key InChIKey=LPCDOMMRICKOBC-JDXGNMNLSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50372114   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372114(CHEMBL404646)
Affinity DataEC50:  40nMAssay Description:Agonist activity at PPARgamma in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372114(CHEMBL404646)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of CYP3A4 in presence of 7-benzyloxyresorufin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372114(CHEMBL404646)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372114(CHEMBL404646)
Affinity DataIC50:  110nMAssay Description:Inhibition of PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372114(CHEMBL404646)
Affinity DataIC50:  650nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372114(CHEMBL404646)
Affinity DataIC50:  520nMAssay Description:Inhibition of PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372114(CHEMBL404646)
Affinity DataEC50:  40nMAssay Description:Agonist activity at PPARalpha in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372114(CHEMBL404646)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed