BDBM50372493 CHEMBL404128

SMILES COc1ccc2c(c1)-c1ccc3cccnc3c1NS2(=O)=O

InChI Key InChIKey=SLHPCVSVVGUJGP-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50372493   

TargetNF-kappa-B inhibitor alpha(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50372493(CHEMBL404128)
Affinity DataEC50:  1.30E+3nMAssay Description:Induction of human IkappaBalpha stabilization in OCI-Ly3 cells by green light emiting IkappaBalpha-fused luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNF-kappa-B inhibitor alpha(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50372493(CHEMBL404128)
Affinity DataEC50:  1.40E+3nMAssay Description:Induction of human IkappaBalpha stabilization in OCI-Ly3 cells assessed as ratio of green light emiting IkappaBalpha-fused luciferase expression to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Columbia University

Curated by ChEMBL
LigandPNGBDBM50372493(CHEMBL404128)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed