BDBM50374211 CHEMBL4173396

SMILES COC(=O)[C@H](Cc1ccc(OC(=O)c2c(C)oc3c2C(=O)c2ncccc2C3=O)cc1)NC(C)=O

InChI Key InChIKey=FKIJJKFQSLEQPF-KRWDZBQOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374211   

TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50374211(CHEMBL4173396)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human TDP2 expressed in TDP2 deficient chicken DT40 whole cell extracts using TY19 DNA as substrate after 15 mins by by PAGE analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50374211(CHEMBL4173396)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of recombinant human TDP2 using TY18 (alpha-[32P]-cordycepin-3'-labeled) as substrate after 15 mins by PAGE analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed