BDBM50375607 CHEMBL259218
SMILES Cc1ccc(Nc2c(Cl)cccc2Cl)c(CC(O)=O)c1
InChI Key InChIKey=ZDDWMWKQAQNCBL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50375607
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataKi: 820nMAssay Description:Inhibition of mouse COX2 pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of human COX2 preincubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of ovine COX1 pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of purified mouse COX-2 assessed as inhibition of PGE2/PGD2 formation preincubated for 3 mins before arachidonic acid substrate addition m...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of purified mouse COX-2 assessed as inhibition of PGE2-G/PGD2-G formation preincubated for 3 mins before 2-AG substrate addition measured ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Vanderbilt Institute For Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair