BDBM50376424 CHEMBL4160763

SMILES Cc1oc2c(c1C(=O)Oc1cccc(N)c1)C(=O)c1ncccc1C2=O

InChI Key InChIKey=MKOXUBRPWVNUIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376424   

TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50376424(CHEMBL4160763)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of recombinant human TDP2 using TY18 (alpha-[32P]-cordycepin-3'-labeled) as substrate after 15 mins by PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50376424(CHEMBL4160763)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human TDP2 expressed in TDP2 deficient chicken DT40 whole cell extracts using TY19 DNA as substrate after 15 mins by by PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed