BDBM50377832 CHEMBL401688

SMILES CC(N1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(NC(=O)CCl)cc1

InChI Key InChIKey=RCYWAXIDQNVCBO-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50377832   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377832(CHEMBL401688)
Affinity DataKi:  493nMAssay Description:Displacement of [3H]ifenprodil from rat brain membrane NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377832(CHEMBL401688)
Affinity DataEC50: >1.00E+5nMAssay Description:Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377832(CHEMBL401688)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of N-terminal domain truncated NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced curren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50377832(CHEMBL401688)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of NR1/NR2B receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed