BDBM50378007 CHEMBL1627315

SMILES COc1ccc2[nH]c(cc2c1)C(=O)NCCC(O)CN1CCN(CC1)c1ccccc1OC

InChI Key InChIKey=SLERETJRSLMXIG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378007   

TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50378007(CHEMBL1627315)
Affinity DataKi:  2.32nMAssay Description:Displacement of [125]IABN from human D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50378007(CHEMBL1627315)
Affinity DataKi:  1.53E+3nMAssay Description:Displacement of [125]IABN from human D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50378007(CHEMBL1627315)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50378007(CHEMBL1627315)
Affinity DataIC50:  1.58nMAssay Description:Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed