BDBM50379361 CHEMBL2011938

SMILES COc1ccc(cc1)-c1nc2ncc(Br)c(NCCCNC(=O)c3cccnc3)c2[nH]1

InChI Key InChIKey=ZEEVDVUFURMNEH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50379361   

TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50379361(CHEMBL2011938)
Affinity DataEC50:  87nMAssay Description:Inhibition of TBK1-mediated NFkappaB activation expressed in ds-RNA activated HEK293 cells coexpressing TLR3 after 4.5 hrs by luciferase reporter gen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed