BDBM50379915 CHEMBL2012070
SMILES CC#Cc1cncc(c1)-c1cccc(c1)[C@]1(N=C(N)N(C)C1=O)C1CC1
InChI Key InChIKey=HORHMTMHXZJNQJ-OAQYLSRUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50379915
Affinity DataKi: 5.40nMAssay Description:Inhibition of human BACE1 using QSY7EISEVNLDAEFC-Eu-amide as substrate incubated for 30 mins prior to substrate addition measured after 90 mins by FR...More data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP swedish and london mutant assessed as decrease of amyloid-beta40 level after 4 hrs by electrochemi...More data for this Ligand-Target Pair