BDBM50380204 CHEMBL2011405::US10406136, Compound 6

SMILES [#6]-[#8]-c1c(-[#8])cc(cc1-[#8])-[#6]-1-[#6]-[#6](=O)-c2c(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc2-[#8]-1

InChI Key InChIKey=GMGRYHOHJJROMP-OVCLIPMQSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50380204   

TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Graduate School Of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50380204(CHEMBL2011405 | US10406136, Compound 6)
Affinity DataKi:  7.60E+3nMAssay Description:Mixed type inhibition of equine BChE using butyrylthiocholine iodide as substrate by Lineweaver-Burk double-reciprocal-plot and dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Graduate School Of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50380204(CHEMBL2011405 | US10406136, Compound 6)
Affinity DataKi:  3.01E+4nMAssay Description:Mixed type inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate by Lineweaver-Burk double-reciprocal-plot and dixon plot ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase(Clostridium perfringens)
Industry-Academic Cooperation Foundation Gyeongsang National University

US Patent
LigandPNGBDBM50380204(CHEMBL2011405 | US10406136, Compound 6)
Affinity DataKi:  1.40E+5nMAssay Description:Specifically, in order to determine IC50 of the compounds for neuraminidase, 0.01 U/ml of neuraminidase (EC. 3.2.1.8, C. perfringens, SIGMA, N2876) a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSialidase(Clostridium perfringens)
Industry-Academic Cooperation Foundation Gyeongsang National University

US Patent
LigandPNGBDBM50380204(CHEMBL2011405 | US10406136, Compound 6)
Affinity DataIC50:  1.90E+5nMAssay Description:Specifically, in order to determine IC50 of the compounds for neuraminidase, 0.01 U/ml of neuraminidase (EC. 3.2.1.8, C. perfringens, SIGMA, N2876) a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetylcholinesterase(Homo sapiens (Human))
Graduate School Of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50380204(CHEMBL2011405 | US10406136, Compound 6)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibition of human erythrocyte AChE assessed as acetylthiocholine iodide hydrolysis after 10 mins preincubation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Graduate School Of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50380204(CHEMBL2011405 | US10406136, Compound 6)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of equine BChE assessed as butyrylthiocholine iodide hydrolysis after 10 mins preincubation by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed