BDBM50382936 CHEMBL2029571
SMILES O[C@]1(CC[C@@H](CC1)N[C@H]1CCN(C1)C(=O)C1CCN(CC1)c1cc(ccn1)C#N)c1ccc(cn1)-c1ncccn1
InChI Key InChIKey=IOTAVZSKYWFPSG-LNFMTQTQSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50382936
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MCP1 from human CCR2 in PBMC after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Antagonist activity at CCR2 receptor in human whole blood assessed as inhibition of alexa-tagged MCP-induced effect 30 mins by flow cytometryMore data for this Ligand-Target Pair