BDBM50383114 CHEMBL2031734
SMILES COc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2cc(CN3CCCC3)cnc2c1C
InChI Key InChIKey=BQVQEXPJBUKTFE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50383114
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.530nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced [3H]arachidonic acid release after 16 hrs by liquid s...More data for this Ligand-Target Pair