BDBM50385376 CHEMBL2036377

SMILES COc1ccc2n(Cc3ccccc3Cl)c(nc2c1)C(C)c1ccc(CC(C)C)cc1

InChI Key InChIKey=JPEJCNWUFQHFCB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385376   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University

Curated by ChEMBL
LigandPNGBDBM50385376(CHEMBL2036377)
Affinity DataIC50:  120nMAssay Description:Inhibition of FLAP in A23187-stimulated human neutrophils assessed as 5-LO product formation preincubated for 15 mins measured after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed