BDBM50385390 CHEMBL2036163
SMILES CC(C)Cc1ccc(cc1)C(C)c1nc2ccccc2n1Cc1ccccc1Cl
InChI Key InChIKey=RSOFSWHYZCGXSL-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50385390
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of FLAP in A23187-stimulated human neutrophils assessed as 5-LO product formation preincubated for 15 mins measured after 10 minsMore data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of FLAP in A23187-stimulated human neutrophils assessed as reduction in 5-LO product formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta human A549 microsome using PGH2 as substrate preincubated for 15 mins followed by substrate addition for 1...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of FLAP in human monocyte assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated with enzyme for 15 mins fol...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of FLAP in human whole blood assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated with enzyme for 15 mins ...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of FLAP in human neutrophil assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation using arachidonic acid as substrate pr...More data for this Ligand-Target Pair