BDBM50386178 CHEMBL1800346::ONO-1714

SMILES C[C@H]1CC(N)=N[C@@H]2[C@H](Cl)[C@H]12

InChI Key InChIKey=SEVICIFJHBFRBO-OXVRIYFGSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50386178   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Instituto Cajal (Csic)

Curated by ChEMBL
LigandPNGBDBM50386178(CHEMBL1800346 | ONO-1714)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Rattus norvegicus)
Instituto Cajal (Csic)

Curated by ChEMBL
LigandPNGBDBM50386178(CHEMBL1800346 | ONO-1714)
Affinity DataKi:  1.80nMAssay Description:Inhibition of rat iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Instituto Cajal (Csic)

Curated by ChEMBL
LigandPNGBDBM50386178(CHEMBL1800346 | ONO-1714)
Affinity DataKi:  1.86nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50386178(CHEMBL1800346 | ONO-1714)
Affinity DataKi:  18.6nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Instituto Cajal (Csic)

Curated by ChEMBL
LigandPNGBDBM50386178(CHEMBL1800346 | ONO-1714)
Affinity DataIC50:  11nMAssay Description:Inhibition of mouse recombinant iNOS activity assessed as conversion of [14C]-L-arginine to [14C]-L-citrulline by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed