BDBM50386271 CHEMBL2040983

SMILES Clc1ccc(CC(=O)N2Cc3ccccc3C[C@@H]2C(=O)Nc2ccc(cc2)N2CCOCC2=O)cc1

InChI Key InChIKey=ZIKSLKHARJRZCC-RUZDIDTESA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50386271   

TargetCoagulation factor X(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50386271(CHEMBL2040983)
Affinity DataIC50:  270nMAssay Description:Inhibition of human factor 10a using chromogenic spectrozyme F10a as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50386271(CHEMBL2040983)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human factor 2a using chromogenic spectrozyme TH as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50386271(CHEMBL2040983)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human factor 7a using chromogenic spectrozyme 7a as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50386271(CHEMBL2040983)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human factor 11a using chromogenic S2366 as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50386271(CHEMBL2040983)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of factor 12a using chromogenic spectrozyme 12a as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50386271(CHEMBL2040983)
Affinity DataIC50:  7.53E+4nMAssay Description:Inhibition of bovine alpha-chymotrypsin using chromogenic spectrozyme CTY as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50386271(CHEMBL2040983)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human factor 9a using chromogenic spectrozyme 9a as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed