BDBM50387556 CHEMBL2057438::US9359372, DC037077
SMILES COc1cc(OC)c2CN3CCc4cc5OCOc5cc4[C@@H]3Cc2c1CO
InChI Key InChIKey=WQKIFVVNHWIOKA-KRWDZBQOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50387556
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Affinity DataKi: 182nM ΔG°: -9.34kcal/mole IC50: 324nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Affinity DataKi: 182nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Affinity DataKi: 600nM ΔG°: -8.62kcal/mole IC50: 758nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Affinity DataKi: 600nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Shanghai Institute of Material Medica, Chinese Academy of Sciences
US Patent
Affinity DataIC50: 324nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair