BDBM50389814 CHEMBL2070705
SMILES NC(=O)Nc1sc(cc1C(=O)N[C@H]1CCCNC1)-c1cc(F)cc(F)c1
InChI Key InChIKey=GDRXUUOZSYPBPT-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50389814
Affinity DataEC50: 1.50E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair