BDBM50390495 CHEMBL2071609

SMILES N#Cc1ccc2nc(Nc3ccc(cc3)-c3ccccc3)[nH]c2c1

InChI Key InChIKey=PIAVBWNWDQQHHF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50390495   

TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390495(CHEMBL2071609)
Affinity DataIC50:  5.49E+3nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform gamma-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390495(CHEMBL2071609)
Affinity DataIC50:  4.89E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390495(CHEMBL2071609)
Affinity DataIC50:  3.08E+4nMAssay Description:Inhibition of GSK3beta by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390495(CHEMBL2071609)
Affinity DataIC50:  2.18E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed