BDBM50390496 CHEMBL2071610

SMILES Fc1ncccc1-c1ccc(Nc2nc3ccc(cc3[nH]2)C#N)cc1

InChI Key InChIKey=VFAPMHXLINRCAL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50390496   

TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390496(CHEMBL2071610)
Affinity DataIC50:  4.67E+3nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform gamma-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390496(CHEMBL2071610)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390496(CHEMBL2071610)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of GSK3beta by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390496(CHEMBL2071610)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed