BDBM50392653 CHEMBL2153707

SMILES Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)ccc2n1

InChI Key InChIKey=FFNKBHOXODTCMK-AWEZNQCLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392653   

TargetMethionine synthase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50392653(CHEMBL2153707)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of methionine synthase in human HL60 cells using L-homocysteine as substrate incubated for 3 hrs prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50392653(CHEMBL2153707)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant DHFR using dihydrofolate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed