BDBM50392906 CHEMBL2152204

SMILES COc1ccc(CCNC(=O)c2ccc(cc2)S(=O)(=O)N2CCC(CC2)NC(=O)C=C)cc1

InChI Key InChIKey=NAKBZGQGRIHKEQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50392906   

TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392906(CHEMBL2152204)
Affinity DataIC50:  110nMAssay Description:Inhibition of human TGM2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase K(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392906(CHEMBL2152204)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human TGM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392906(CHEMBL2152204)
Affinity DataIC50:  110nMAssay Description:Ability to inhibit U-46,619-induced contraction of isolated strips of rat aorta, which is the measure of thromboxane receptor antagonismMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCoagulation factor XIII A chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392906(CHEMBL2152204)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human factor-13AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50392906(CHEMBL2152204)
Affinity DataIC50:  55nMAssay Description:Inhibition of mouse TGM2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392906(CHEMBL2152204)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human TGM6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed