BDBM50393092 CHEMBL2152907

SMILES CN1C(=O)CC2(N=C1N)[C@H]1CCC3(CC1Oc1ccc(cc21)-c1cc(F)cc(Cl)c1)OCCO3

InChI Key InChIKey=GDKALKZMSYCZMM-HHIIEYADSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393092   

TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393092(CHEMBL2152907)
Affinity DataIC50:  3.08E+3nMAssay Description:Inhibition of BACE1-mediated amyloid beta (1 to 40) production after 48 hrs by cell based HTRF immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed