BDBM50393093 CHEMBL2152909

SMILES NC1=N[C@@]2(CO1)[C@H]1C[C@H](COC1Oc1ccc(cc21)-c1cncc(Cl)c1)OCC1CC1

InChI Key InChIKey=ZPBOQODCXCRRAT-JGMWDMSASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393093   

TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393093(CHEMBL2152909)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of BACE1-mediated amyloid beta (1 to 40) production after 48 hrs by cell based HTRF immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed