BDBM50395399 CHEMBL2165063

SMILES COc1ccc2ncc(=O)n(CCN3CCC(CC3)NCc3ccc4OCC(=O)Nc4n3)c2c1

InChI Key InChIKey=VQECILSOQQFMKP-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50395399   

LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel HCN4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of potassium channel Cav3.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50:  9.20E+4nMAssay Description:Inhibition of potassium channel Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of potassium channel IKs (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human ERG by Ionworks assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395399(CHEMBL2165063)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed