BDBM50395400 CHEMBL2165062

SMILES O=c1ccc2ccc(cc2n1CCN1CCC(CC1)NCc1cc2OCCOc2cn1)C#N

InChI Key InChIKey=SEYRFRYGJGGXBD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395400   

TargetDNA gyrase subunit B(Mycobacterium smegmatis)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395400(CHEMBL2165062)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase-B ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395400(CHEMBL2165062)
Affinity DataIC50:  3.90E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395400(CHEMBL2165062)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human ERG by Ionworks assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395400(CHEMBL2165062)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human ERG by patch clamp electrophysiological analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed