BDBM50396352 CHEMBL2170062
SMILES Cc1cc(OCCN2CCOCC2)nn1-c1ccc2ccccc2c1
InChI Key InChIKey=DGPGXHRHNRYVDH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50396352
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 180 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]pentazocine from human sigma 1 receptor expressed in HEK293 cell membrane incubated for 2 hrs by liquid scintillation counting me...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma-1 receptor transfected in HEK293 membranes incubated for 120 mins measured by microBeta scintil...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H](+)pentazocine from human sigma 1 receptor transfected in HEK293 cell membranes after 120 mins by scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor transfected in HEK293 cell membranes assessed as inhibition constant measured after 1...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma-1 receptor expressed in HEK293 membranes incubated for 120 mins by liquid scintillation countin...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-(+)-pentazocine from recombinant human sigma1 receptor expressed in HEK293 cell membranes after 120 mins by microbeta scintillat...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Binding affinity to human sigma-1 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of 3H](+)-pentazocine from human sigma1 receptor expressed in HEK293 cell membranes incubated for 120 mins by liquid scintillation count...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor expressed in HEK293 cell membranes incubated for 120 mins by liquid scintillation cou...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-pentazocine from sigma-1 receptor in human Jurkat cell membrane incubated for 2 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 328nMAssay Description:Binding affinity to human 5HT2B receptorMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against porcine plasma Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendor
Curated by ChEMBL
Affinity DataKi: 9.30E+3nMAssay Description:Displacement of (+)-[3H]DTG from sigma 2 receptor in SPRD rat liver membrane incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHOK1 cell membranes incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHOK1 cell membranes incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 60 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair