BDBM50396956 CHEMBL2170964

SMILES Fc1ccc(cc1)-c1cnc2nnc(COc3ccnc4ccsc34)n2n1

InChI Key InChIKey=DZWZUPWXIBCAEV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396956   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50396956(CHEMBL2170964)
Affinity DataKi:  425nMAssay Description:Competitive inhibition of N-terminal His6-tagged recombinant human c-MET (974 to 1390 amino acids) by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50396956(CHEMBL2170964)
Affinity DataIC50: >2.50E+3nMAssay Description:Antagonist activity at c-MET receptor in human A549 cells assessed as inhibition of autophosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed