BDBM50397292 CHEMBL454890::VUF-10499
SMILES CN1CCN(CC1)c1nc(NCc2ccoc2)c2cc(Cl)ccc2n1
InChI Key InChIKey=VCADIWSEVTZZOR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50397292
Affinity DataKi: 2.82nMAssay Description:Displacement of [3H]granisetron from 5HT3A receptor expressed in HEK293 cells after 24 hrs by scintillation counting in presence of quipazineMore data for this Ligand-Target Pair
Affinity DataKi: 24.6nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 26.9nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 89.1nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 97.7nMAssay Description:Displacement of [3H]mepyramine from human histamine H1 receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Inverse agonist activity at human histamine H4 receptor expressed in HEK293T cells by CRE-beta-galactosidase assayMore data for this Ligand-Target Pair