BDBM50398295 CHEMBL2177311
SMILES COc1ccc(cc1)C1(COC(N)=N1)c1cccc(c1)-c1cccc(Cl)c1
InChI Key InChIKey=METABQXTPBWILS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50398295
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP Swedish mutant assessed as reduction in amyloid beta 40 production after overnight incubatio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of human recombinant BACE1 using Glu-Ile-Asp-Leu-Met-Val-Leu-Asp as substrate incubated for 60 mins prior to substrate addition measured a...More data for this Ligand-Target Pair