BDBM50398777 CHEMBL2180026

SMILES COc1ccc(cc1)C1(N=C(C)C(N)=N1)c1cccc(c1)-c1cccnc1

InChI Key InChIKey=PHOHQSLNKFJNQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398777   

TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50398777(CHEMBL2180026)
Affinity DataIC50:  810nMAssay Description:Inhibition of BACE1-mediated sAPPbeta release in human SH-SY5Y cells after 16 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50398777(CHEMBL2180026)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50398777(CHEMBL2180026)
Affinity DataIC50:  330nMAssay Description:Inhibition of human BACE1 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after 15 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed