BDBM50398788 CHEMBL2180022

SMILES CC1=NC(N=C1N)(c1ccccc1)c1cccc(c1)-c1cccnc1

InChI Key InChIKey=TVFLMALGICYVSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398788   

TargetBeta-secretase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50398788(CHEMBL2180022)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of BACE1-mediated sAPPbeta release in human SH-SY5Y cells after 16 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50398788(CHEMBL2180022)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human BACE1 using (europium)CEVNLDAEFK(Qsy7) as substrate incubated for 10 mins prior to substrate addition measured after 15 mins by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed