BDBM50398935 PROPYLPYRAZOLETRIOL

SMILES CCCc1c(nn(c1-c1ccc(O)cc1)-c1ccc(O)cc1)-c1ccc(O)cc1

InChI Key InChIKey=IOTXSIGGFRQYKW-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398935   

TargetEstrogen receptor(Homo sapiens (Human))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50398935(PROPYLPYRAZOLETRIOL)
Affinity DataEC50:  3nMAssay Description:Activation of ERalpha in human MCF7/2a cells by luciferase reporter gene assay relative to untreated controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50398935(PROPYLPYRAZOLETRIOL)
Affinity DataEC50:  1nMAssay Description:Estrogenic activity at ERalpha in human Ishikawa cells assessed as induction of alkaline phosphatase activity using p-nitrophenol as substrate treate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50398935(PROPYLPYRAZOLETRIOL)
Affinity DataEC50:  0.100nMAssay Description:Activation of human ERalpha expressed in human U2-OS cells by luciferase reporter gene assay relative to untreated controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed