BDBM50400097 CHEMBL2177118

SMILES COC(=O)c1cccc(NC(=O)CCOc2ccc(cc2)C23CC4CC(CC(C4)C2)C3)c1

InChI Key InChIKey=DCWZGVZXOAEXSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400097   

TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50400097(CHEMBL2177118)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of HIF1alpha in human HCT116 cells under hypoxic condition after 16 hrs by dual luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed