BDBM50400541 CHEMBL2204950

SMILES COc1cccc(CNC(=O)N[C@@H](CC(C)C)C(=O)NO)c1

InChI Key InChIKey=VRQZXSUCWGBJIY-ZDUSSCGKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50400541   

TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50400541(CHEMBL2204950)
Affinity DataIC50:  290nMAssay Description:Inhibition of APN in porcine kidney microsome assessed as inhibition of L-Leu-p-nitroanilide substrate hydrolysis incubated for 5 mins before substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400541(CHEMBL2204950)
Affinity DataIC50:  790nMAssay Description:Inhibition of APN in human ES2 cell surface assessed as inhibition of L-Leu-p-nitroanilide substrate hydrolysis incubated for 5 mins before substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400541(CHEMBL2204950)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant MMP-2 using succinylated gelatin as substrate incubated for 10 mins before addition of substrate measured after 60 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50400541(CHEMBL2204950)
Affinity DataIC50:  5.61E+3nMAssay Description:Inhibition of mouse APNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed