BDBM50400773 CHEMBL2204984

SMILES CCc1cnc(nc1)N1CCC(CC1)n1ncc(COc2ccc(cc2)-n2cnnn2)c1C#N

InChI Key InChIKey=BGLRWXCBFWYRFO-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50400773   

TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400773(CHEMBL2204984)
Affinity DataKi:  15nMAssay Description:Binding affinity to human GPR119More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400773(CHEMBL2204984)
Affinity DataEC50:  11nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as cAMP level by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400773(CHEMBL2204984)
Affinity DataEC50:  5.30nMAssay Description:Agonist activity at GPR119 in human U20S cells assessed as binding to beta-arrestin by chemilumiscence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed