BDBM50400986 CHEMBL1550905

SMILES [O-][N+](=O)c1cccc(c1)S(=O)(=O)n1cccc1\C=C(/C#N)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=GUCUORSUHTZMBW-YBFXNURJSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50400986   

TargetProtein phosphatase methylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50400986(CHEMBL1550905)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of PME1 binding to FP-rhodamine in HEK293T cells after 1 hr by fluorescence polarization activity-based protein profiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase methylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50400986(CHEMBL1550905)
Affinity DataIC50:  600nMAssay Description:Inhibition of PME1 binding to FP-rhodamine in human HEK293T cells after 45 mins by fluorescence polarization activity-based protein profiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase methylesterase 1(Mus musculus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50400986(CHEMBL1550905)
Affinity DataIC50:  600nMAssay Description:Inhibition of PME1 binding to FP-rhodamine in mouse brain soluble proteome after 45 mins by fluorescence polarization activity-based protein profilin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed