BDBM50401152 CHEMBL2205766
SMILES CC(C)(C)NS(=O)(=O)c1cncc(c1)-c1ccn2nc(N)nc2c1
InChI Key InChIKey=IVYWKCAOPCHVMX-UHFFFAOYSA-N
Data 164 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 164 hits for monomerid = 50401152
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CK2a2More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of PI3Kgamma by kinobeads assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PRKD2More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PRKCAMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PIK3CbMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAPK8More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of EIF2AK4More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of AURKBMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CAMKK2More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of CDC2More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 2.00E+7nMAssay Description:Inhibition of PI3Kalpha assessed as change in pIC50 by kinobeads assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ATMMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 5.01E+7nMAssay Description:Inhibition of PIK3CdMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of BRD4More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of BRD3More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of BRD2More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of BRAFMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of BMPR1AMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of BMP2KMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of BLKMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of AURKAMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ARAFMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ADCK4More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ACVR2BMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ACVR2AMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ACVR1BMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ACVR1More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ABL2More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ABL1More data for this Ligand-Target Pair
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of PIP4K2CMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of PIK3CaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair
Affinity DataIC50: 5.89E+3nMAssay Description:Inhibition of AAK1More data for this Ligand-Target Pair
Affinity DataIC50: 9.12E+3nMAssay Description:Inhibition of CSNK1A1More data for this Ligand-Target Pair
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of PAK4More data for this Ligand-Target Pair
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of CSNK1G1More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: 5.01E+7nMAssay Description:Inhibition of PIK3CbMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 3(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAP3K3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 2(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAP3K2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAP3K11More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 1(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAP3K1More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 5(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAP2K5More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAP2K2More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Cellzome
Curated by ChEMBL
Cellzome
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAP2K1More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of LIMK2More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair