BDBM50401325 CHEMBL2205228

SMILES CCc1cc2n(C)c(C(=O)NC3CCN(CC3)C(=O)CO)c(OCCF)c2c(=O)n1CC(=O)c1ccccc1

InChI Key InChIKey=VTSRALROELUIJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401325   

TargetSonic hedgehog protein(Mus musculus (Mouse))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401325(CHEMBL2205228)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of recombinant mouse Shh-N expressed in mouse NIH3T3/Gli-luc cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed