BDBM504015 (1S,2S,3R)N-[8-amino-6-(4-methylpyridin-3-yl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)-3-methylcyclopropane-1-carboxamide (Compound 276) ::US11034692, Compound 279
SMILES C[C@@H]1[C@@H](CC#N)[C@@H]1C(=O)Nc1cc2cc(nc(N)c2cn1)-c1cnccc1C
InChI Key InChIKey=GTAWSJIGHMQLDW-BBEGDGIKSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 504015
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.188nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair