BDBM50401899 CHEMBL2207208

SMILES Cn1cc(Nc2ncc(C3CC3)c(NCCCNC(=O)C3CCC3)n2)cn1

InChI Key InChIKey=YOFJPZPGHXWQJB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50401899   

TargetAurora kinase B(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401899(CHEMBL2207208)
Affinity DataIC50:  190nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401899(CHEMBL2207208)
Affinity DataIC50:  100nMAssay Description:Inhibition of IKKepsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401899(CHEMBL2207208)
Affinity DataIC50:  110nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Mus musculus)
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401899(CHEMBL2207208)
Affinity DataIC50:  170nMAssay Description:Inhibition of TBK1-mediated RANTES release in LPS-stimulated mouse RAW264.7 cells compound incubated for 30 mins prior LPS challenge measured after 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401899(CHEMBL2207208)
Affinity DataIC50:  20nMAssay Description:Inhibition of MARK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401899(CHEMBL2207208)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of MNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401899(CHEMBL2207208)
Affinity DataIC50:  8nMAssay Description:Inhibition of TBK1 by radiometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase BRSK2(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50401899(CHEMBL2207208)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of BRSK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed