BDBM50402484 CHEMBL2204057

SMILES Cc1cccc(Cc2c([nH]c(=O)[nH]c2=O)[C@@H]2CC[C@@H](CC2)c2ccccc2)n1

InChI Key InChIKey=BWSXTKUBVPLPRK-HDICACEKSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402484   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50402484(CHEMBL2204057)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus after 18 hrs by scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50402484(CHEMBL2204057)
Affinity DataKi:  57nMAssay Description:Antagonist activity at glucocorticoid receptor in human SW1353 cells assessed as inhibition of dexamethasone-induced luciferase expression after 16 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed