BDBM50403074 CHEMBL2216903

SMILES CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(OC3CN(C3)C(=O)C(C)C)n(C)c2n1

InChI Key InChIKey=KDXGIMDDVFVVKU-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50403074   

LigandPNGBDBM50403074(CHEMBL2216903)
Affinity DataKi:  0.576nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403074(CHEMBL2216903)
Affinity DataKi:  0.580nMAssay Description:Inhibition of PI3Kdelta (unknown origin) assessed as formation of PIP3 by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403074(CHEMBL2216903)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as inhibition of CD69 production in B lymphocyte by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403074(CHEMBL2216903)
Affinity DataIC50:  12nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as expression of CD69 in B cell preincubated for 1 hr by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed