BDBM50404889 CHEMBL303714

SMILES NCc1nc2ccccc2[nH]1

InChI Key InChIKey=UCOSRTUSVXHIMK-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50404889   

TargetMembrane primary amine oxidase(Rattus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-3(Mus musculus)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50:  0.0280nMAssay Description:Cytotoxicity against human NB-1 cells by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase in cell free Quan-T-RT by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50:  4.57E+5nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed