BDBM50408219 CHEMBL4165369

SMILES Fc1ccc(Cn2cc(Br)c(-c3ccccc3)c(C(=O)NC3CCCCCC3)c2=O)cc1

InChI Key InChIKey=ASMJTPOFWQZVFN-UHFFFAOYSA-N

Data  2 KI  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50408219   

TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataKi:  437nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cells using AEA containing [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cells using 2-OG containing [glycerol-1,2,3-3H]AEA as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidylserine lipase ABHD12(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50408219(CHEMBL4165369)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed