BDBM50415643 CHEMBL1078642::UR-PI376

SMILES N#CNC(NCCSc1ccccc1)=NCCCCc1cnc[nH]1

InChI Key InChIKey=DHHDEHNHEBYRPQ-UHFFFAOYSA-N

Data  4 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50415643   

TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415643(CHEMBL1078642 | UR-PI376)
Affinity DataKi:  57.5nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415643(CHEMBL1078642 | UR-PI376)
Affinity DataKi:  525nMAssay Description:Displacement of [3H]N-alpah-methylhistamine from human histamine H3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415643(CHEMBL1078642 | UR-PI376)
Affinity DataKi:  4.07E+3nMAssay Description:Displacement of [3H]tiotidine from human histamine H2 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415643(CHEMBL1078642 | UR-PI376)
Affinity DataKi:  2.57E+4nMAssay Description:Displacement of [3H]mepyramine from human histamine H1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415643(CHEMBL1078642 | UR-PI376)
Affinity DataEC50:  33.9nMAssay Description:Agonist activity at human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19 protein by steady-state GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415643(CHEMBL1078642 | UR-PI376)
Affinity DataEC50:  720nMAssay Description:Agonist activity at human histamine H3 receptor expressed in sf9 cell membrane co-expressing mammalian Galphai2 and Gbeta1gamma2 incubated for 90 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50415643(CHEMBL1078642 | UR-PI376)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human histamine H4 receptor expressed in sf9 cell membrane co-expressing mammalian Galphai2 and Gbeta1gamma2 incubated for 90 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed