BDBM50424403 CHEMBL2315074

SMILES Nc1ncc(-c2cccnc2)c2scc(-c3cccc(NC(=O)NC4CCCCC4)c3)c12

InChI Key InChIKey=ORVLYSPTAVNDEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424403   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50424403(CHEMBL2315074)
Affinity DataIC50:  31nMAssay Description:Inhibition of B-Raf (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50424403(CHEMBL2315074)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of B-Raf (unknown origin) expressed in mouse 3T3 cells co-expressing FLAG-tagged MEK1 assessed as inhibition of MEK1 phosphorylation after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed