BDBM50424584 CHEMBL2312530

SMILES OC(=O)Cc1csc(=NC(=O)CS(=O)(=O)Cc2ccc3ccccc3c2)n1O

InChI Key InChIKey=QNCNQHCDQMPPGD-UHFFFAOYSA-N

Data  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50424584   

TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50424584(CHEMBL2312530)
Affinity DataIC50:  20nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50424584(CHEMBL2312530)
Affinity DataKd:  110nMAssay Description:Displacement of [13C]-2OG from catalytic domain of PHD2 (181 to 426) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50424584(CHEMBL2312530)
Affinity DataKd:  100nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed