BDBM50424917 CHEMBL2311578

SMILES Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=UJGTUKMAJVCBIS-UHFFFAOYSA-N

Data  2 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50424917   

TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424917(CHEMBL2311578)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant His-GST tagged VCP expressed in baculovirus infected Hi5 cells assessed as ADP formation incubated for 20 mins proir ...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424917(CHEMBL2311578)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human full length Avi-tagged p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2(DE3) using 100 uM ATP as subst...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424917(CHEMBL2311578)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of human p97 in human HeLa cells harboring UbG76V-GFP assessed as accumulation of UbG76V after 1 hr by microscopic analysisMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50424917(CHEMBL2311578)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of human p97 in human HeLa cells harboring UbG76V-GFP assessed as accumulation of UbG76V after 6 hrs by microscopic analysisMore data for this Ligand-Target Pair